GENETICS & OMICS
Dr Laura Fachal (Wellcome Sanger Institute, UK) has played a pivotal role in supporting this section
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2011 GWAS loci identifies independent rare variants associated with IBD
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease -
2010 GWAS identifies multiple susceptibility loci in UC
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2010 GWAS identifies 71 loci associated to CD susceptibility (including SMAD3, ERAP2, IL10, IL2RA, TYK2, FUT2, DNMT3A, DENND1B, BACH2, TAGAP)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn’s disease susceptibility loci -
2009 Three new susceptibility loci for UC susceptibility in Japanese
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population -
2009 JAK2 (IBD), LYRM4 and CDKAL1 (UC) and more in CD
Investigation of Crohn’s Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship -
2009 IBD among danish twins
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2009 GWAS of UC susceptibility loci
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region -
2009 Genetic variants in the region harbouring IL2/IL21 associated with UC
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2008 ECM1 locus in UC
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn’s disease -
2007 IL23R, ATG16L1 & 5p13.1-CD Japan
Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn’s disease in Japanese patients