Timeline

Step into the IBD Timeline and embark on a journey through the chronological milestones, breakthroughs, and significant studies that have shaped the understanding and treatment of IBD. Explore the evolution of research, therapies, and key discoveries that have paved the way for advancements in IBD care.

Coming soon…
List with the upcoming studies

ACCURE

ACCURE-UK

COSTA

SEQUENCE

PROFILE

STATIC

IASO

REPREVIO

SOPRANO-CD

MEERKAT

SPICY

TITRATE

TRIBUTE

COMBINE

COMMET

TENOR

QUASAR

UNIFI Jr

DUMBO

PREdiCCt

IVEMEI

JUNIPER

SERENITY

NOR-DRUM B

COTTONWOOD

INTREPID

ELDERLUST

RESERVO

VERSUS CD

LOVE-UC

EXPLORER

EXPEDITION

AMBER 2

BIOSCOPE

PREVEDO

PROFUST

VERDICT

CD HOPE

DIETOMICS CD

GRAVITI

CONCLUDE

DUET UC

POWER

SEMI-VEG

PIONIR

MELODY

VALUE

OATS

CD-TDI

PROACTIVE

ADDapt

LIBERTY-UC

LIBERTY-CD

CD-TREAT

IBD-FITT

ACHILLES

LATTICE-UC

USTAP

DIVERSITY

YELLOWSTONE

and many more

2024
ASTIClite

Safety and efficacy of autologous haematopoietic stem-cell transplantation with low-dose cyclophosphamide mobilisation and reduced intensity conditioning versus standard of care in refractory Crohn’s disease (ASTIClite): an open-label, multicentre, randomised controlled trial

See original study

See summary

COCONUT WATER-UC

Coconut water vs placebo in active mild-moderate UC patients on standard medication

See original study

See summary

ENTERPRET

A Randomized Controlled Trial of Vedolizumab Dose Optimization in Patients With Ulcerative Colitis Who Have Early Nonresponse

See original study

See summary

LIBERTY-UC/CD

Subcutaneous Infliximab (CT-P13 SC) as Maintenance Therapy for Inflammatory Bowel Disease: Two Randomized Phase 3 Trials

See original study

See summary

PROFILE

A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial

See original study

See summary

PROTECT 1/2

Modified-Release Phosphatidylcholine (LT-02) for Ulcerative Colitis: Two Double-Blind, Randomized, Placebo-Controlled Trials

See original study

See summary

Reverse-engineered EEN

Reverse-engineered exclusive enteral nutrition in pediatric Crohn’s disease: A pilot trial

See original study

See summary

2024
2023
TACOS

Tofacitinib in acute severe ulcerative colitis

See original study

See summary

GALAXI-1

Phase 2 trial, guselkumab in Crohn’s disease efficacy and safety at week 48

See original study

See summary

The decider study

Allopurinol-thiopurine versus standard thiopurine in patients with IBD

See original study

See summary

OTC multivitamin/mineral supplement

Over-the-Counter Multivitamin and Mineral Supplement to Prevent Infections in IBD Patients

See original study

See summary

5ASA MMX kids

Mesalamine multimatrix in pediatric UC

See original study

See summary

EXPLORER

Vedolizumab, adalimumab and methotrexate combination in CD

See original study

See summary

U-ACHIEVE maintenance

Upadacitinib maintenance in moderate-severe UC

See original study

See summary

VIBRATO

Ritlecitinib and Brepocitinib in moderate-severe UC

See original study

See summary

Vagus nerve stimulation

Neuroimmune modulation through vagus nerve stimulation in CD

See original study

See summary

ORCHID

Tofacitinib vs oral prednisolone in moderately active UC

See original study

See summary

MCP-UC

Mercaptopurine in UC for maintenance

See original study

See summary

POPEYE

Ferric carboxymaltose vs Ferrous fumarate in Anemic children with IBD

See original study

See summary

COMBINE

Methotrexate combination pediatric CD

See original study

See summary

LUCENT 1 & 2

Mirikizumab induction and maintenance

See original study

See summary

Curcumin-QingDai

Curcumin and QingDai for induction of remission in UC

See original study

See summary

U-EXCEL;U-EXCEED; U-ENDURE

Upadacitinib in Crohn’s disease induction and maintenance

See original study

See summary

Mediterranean diet

Mediterranean Diet vs Canadian diet in quiescent UC

See original study

See summary

LAG-3 depleting Ab

LAG-3 depleting antibody GSK2831781 in UC

See original study

See summary

Olamkicept

Olamkicept induction in ulcerative colitis

See original study

See summary

DIVERGENCE 1

Filgotinib in small bowel Crohn’s disease

See original study

See summary

EARNEST

Vedolizumab in chronic pouchitis

See original study

See summary

ELEVATE
RUN-CD

Ustekinumab vs Infliximab in CD

See original study

See summary

VEDOKIDS

Vedolizumab in children with IBD

See original study

See summary

SPARE

Infliximab or azathioprine withdrawal in CD

See original study

See summary

VEGA

Golimumab, Guselkumab or both in UC

See original study

See summary

BERGAMOT

Etrolizumab induction and maintenance in CD

See original study

See summary

LADI

Adalimumab increased interval in CD

See original study

See summary

SLRIPS

Diverting ileostomy closure after pouch construction

See original study

See summary

BETA-FRUCTANS

Beta-fructan fibers impact in IBD

See original study

See summary

Ritlecitinib-brepocitinib

Ritlecitinib and Brepocitinib in UC

See original study

See summary

5ASA CD

5-ASA in CD maintenance

See original study

See summary

2022
Protdilat

Self-expandable metal stents vs endoscopic balloon dilation for the treatment of strictures in Crohn’s disease

See original study

See summary

U-ACHIEVE & U-ACCOMPLISH

Upadacitinib in UC induction and maintenance

See original study

See summary

AID vs CFG -UC

Anti-Inflammatory Diet Prevents Subclinical Colonic Inflammation and Alters Metabolomic Profile of UC in Clinical Remission

See original study

See summary

5HTP-fatigue

5-Hydroxytryptophan on fatigue in quiescent IBD

See original study

See summary

CDED-AD

The Crohn’s disease exclusion diet for induction and maintenance of remission in CD

See original study

See summary

LOTUS

Lyophilised oral microbiota transplantation for UC

See original study

See summary

ABX464-OBEFAZIMOD

Obefazimod in mod-severe UC

See original study

See summary

FMT-AID

Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) in UC induction and maintenance

See original study

See summary

PIANO registry

Steroid exposure and perinatal outcomes

See original study

See summary

AAUC

Low-dose azathioprine and allopurinol in UC

See original study

See summary

LAUREL

Etrolizumab for maintenance of remission in UC

See original study

See summary

HICKORY

Etrolizumab for induction & maintenance of remission in UC

See original study

See summary

HIBISCUS I&II

Etrolizumab vs adalimumab in UC

See original study

See summary

STARDUST

Ustekinumab in CD. Treat to target or standard of care

See original study

See summary

TISkids

Infliximab vs conventional therapy in pediatric CD

See original study

See summary

SUSTAIN
GALAXI 1
SEAVUE

Ustekinumab vs adalimumab in CD

See original study

See summary

SERENE-UC

Adalimumab eow vs ew in UC

See original study

See summary

SERENE-CD

Adalimumab eow vs ew in CD

See original study

See summary

REMSWITCH

Infliximab IV to SC in IBD

See original study

See summary

COMBO-MESA

Corticosteroids +/- mesalazine in ASUC

See original study

See summary

CRAFT-UC

FMT and/or UCED in UC

See original study

See summary

STOP-IT

Stop infliximab in CD

See original study

See summary

VISIBLE 2

Vedolizumab SC in CD

See original study

See summary

ERIca

Barrier healing in IBD

See original study

See summary

ENTERPRISE

Vedolizumab in perianal CD

See original study

See summary

ADVANCE & MOTIVATE

Risankizumab in CD

See original study

See summary

FORTIFY

Risankizumab maintenance of remission in CD

See original study

See summary

TOUR
VIP

COVID vaccine response in IBD on different drugs

See original study

See summary

AJM300
HUBBLE

Vedolizumab in paediatric IBD

See original study

See summary

PUCCINI

AntiTNF impact on IBD surgery

See original study

See summary

PISA-II

AntiTNF and surgery in perianal CD

See original study

See long term data

See summary

Mirikizumab-ph2-CD

Mirikizumab phase 2 in CD

See original study

See summary

Surgery and antiTNF perianal CD

Surgical closure, mainly with glue injection and anti-tumour necrosis factor α, in perianal CD

See original study

See summary

Spesolimab

Safety and tolerability of spesolimab in UC

See original study

See summary

2022
2021
SELECTION
Low fat high fibre diet UC

Low-Fat, High-Fiber Diet Reduces Markers of Inflammation and Dysbiosis and Improves Quality of Life in UC

See original study

See summary

EEN in UC

Exclusive enteral nutrition in ASUC

See original study

See summary

TRUE NORTH
DINE-CD

Mediterranean diet or Simple Carbohydrate Diet in CD

See original study

See summary

GARDENIA

Etrolizumab vs infliximab in UC

See original study

See summary

CLARITY

COVID infection in IBD

See original study

See summary

UNISTAR

Ustekinumab in paediatric CD

See original study

See summary

TOUCHSTONE-OLE
OASIS-OLE
ENVISION I

Adalimumab in paediatric UC

See original study

See summary

STRIDENT

Adalimumab high dose+azathioprine vs ADA alone in CD strictures

See original study

See summary

FUTURE
RIVETING

Tofacitinib dose reduction in UC

See original study

See summary

VOLTAIRE-CD

Adalimumab originator vs biosimilar in CD

See original study

See summary

IFX IV/SC

IFX IV vs SC in IBD

See original study

See summary

PRECISION
NOR-DRUM A

IFX induction TDM or standard of care

See original study

See summary

NOR-DRUM B

IFX maintenance TDM or standard of care

See original study

See summary

2020
VISIBLE 1

Vedolizumab IV vs SC in UC

See original study

See summary

CELEST
U-ACHIEVE

Upadacitinib in UC

See original study

See summary

CONCEIVE

Pregnancy safety of antiTNF and vedolizumab

See original study

See summary

PISA-I

Seton, antiTNF and/or surgery in perianal CD

See original study

See summary

STEPSTONE
CONDUCT
OASIS
PIANO

Pregnant women with IBD drug safety

See original study

See summary

I6T-MC-AMAC
PRASCO

Atibiotic combo in pediatric ASUC

See original study

See summary

PRESENCE

EEN in pediatric CD

See original study

See summary

SUPREME-CD

Kono-S vs stapled anastomosis in CD

See original study

See summary

AZA to avoid A-D-Ab

2º antiTNF +/- Azathioprine in IBD patients who had immune mediated LOR to first antiTNF

See original study

See summary

TACRO/BECLO

Tacrolimus suppositories vs beclomethasone suppositories in proctitis

See original study

See summary

SCD diet ped-CD

Specific Carbohydrate Diet and Diet Modification as Induction Therapy for Pediatric CD

See original study

See summary

Mirikizumab-phase2 UC

Mirikizumab phase 2 trial in UC

See original study

See summary

Low FODMAP-IBD

Low FODMAP trial on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease

See original study

See summary

2020
2019
UNIFI
PANTS

AntiTNF failure in CD

See original study

See summary

VARSITY

Vedolizumab vs adalimumab in UC

See original study

See summary

VERSIFY
LOVE-CD
CDED+PEN

Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial

See original study

See summary

FACES

Meat consumption in CD

See original study

See summary

PAILOT

Adalimumab in pediatric CD

See original study

See summary

DIAMOND 2

Adalimumab +/- azathioprine stop  CD

See origininal study

See summary

PLANET CD

IFX originator or CT-P13 in CD

See original study

See summary

Abrilumab
ADA-pouchitis

Adalimumab in chronic pouchitis

See original study

See summary

2018
INDIGO NATURALIS

Indigo naturalis in UC

See original study

See summary

IFX postop

Infliximab in postoperative recurrence in CD

See original study

See summary

TEDDY

Newborn exposed to antiTNF safety

See original study

See summary

MERIT-UC

Methotrexate in UC

See original study

See summary

OPERA

anti-MAdCAM antibody PF-00547659 in CD

See original study

See summary

TAILORIX

Infliximab increase dose in CD

See original study

See summary

ATICCA

Granulocyte/Monocyte Apheresis in UC

See original study

See summary

SECURE

IFX originator to CT-P13 in IBD

See original study

See summary

BUDEFOAM

Budesonide foam in left and extensive UC

See original study

See summary

ADMIRE-CD

Stem cell therapy for perianal disease

See original study

See summary

Budesonide-CD

Budesonide in Japanase patients with CD

See original study

See summary

2018
2017
MUPPIT

Once- Versus Twice-daily Mesalazine to Induce Remission in Paediatric Ulcerative Colitis: A Randomised Controlled Trial

See original study

See summary

Risankizumab ph2-cd

Phase 2 trial Risankizumab in Crohn’s disease

See original study

See summary

no-carrageenan diet UC

Effect of no-carrageenan diet in UC activity

See original study

See summary

Multidonor FMT

Multidonor intensive fecal microbiota transplantation in UC

See original study

See summary

CREOLE

Adalimumab in stricturing CD

See original study

See summary

CALM

Adalimumab +/- azathioprine tight control vs clincal management in CD

See original study

See summary

ENCORE-CD

Infliximab in CD safety

See original study

See summary

NOR-SWITCH

CT-P13 or infliximab originator in immune mediated inflammatory diseases

See original study

See summary

OCTAVE 1&2
EXTEND
LIR!C

Infliximab or surgery in ileal CD

See original study

Long-term data 2020

See summary

FITZROY
GOLI kids

Golimumab in pediatric UC

See original study

See summary

APPRECIA

ADA vs AZA in postop recurrence in CD

See original study

See summary

TOPIC TACRO

Topical tacrolimus in UC proctitis

See original study

See summary

EEN in CD

EEN in complicated CD

See original study

See summary

Budesonide- CD Japan

Efficacy and Safety of Oral Budesonide in Patients with Active

Crohn’s Disease in Japan: A Multicenter, Double-Blind,

Randomized, Parallel-Group Phase 3 Study

See original study

See summary

2016
UNITI I&II
DIAMOND

Adalimumab +/- azathioprine in CD

See original study

See summary

COLLECT
ADMIRE-CD

Allogeneic adipose-derived mesenchymal stem cells (Cx601) in perianal CD

See original study

See summary

CONSTRUCT

Infliximab vs cyclosporine in ASUC

See original study

See summary

METEOR

Methotrexate in UC

See original study

See summary

ART

Granulocyte/Monocyte Apheresis in UC

See original study

See summary

TOPPIC

Mercaptopurine in postoperative recurrence CD

See original study

See summary

PREVENT

Infliximab in postoperative recurrence CD

See original study

See summary

Australian vs low FODMAP diet

Consistent Prebiotic Effect on Gut Microbiota With Altered FODMAP Intake in Patients with CD

See original study

See summary

IGG4-exclusion diet

Treatment of CD with an IgG4-Guided Exclusion Diet

See original study

See summary

2016
2015
ASTIC

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease

See original study

See summary

REACT

Early combo (antiTNF+antimetabolite) treatment vs conventional in CD

See original study

See summary

TAXIT

Infliximab dosage in IBD

See original study

See summary

PURSUIT-IV

Intravenous golimumab induction therapy for ulcerative colitis

See original study

See summary

POCER

Post operative recurrence in CD active care or standard care

See original study

See summary

MTX kids SC/PO

Methotrexate in pediatric CD

See original study

See summary

Thalidomide kids UC

Thalidomide in pediatric UC

See original study

See summary

VSL3 postop

VSL3 in postoperative recurrence in CD

See original study

See summary

BUDEFOAM

Budesonide foam for distal UC

See original study

See summary

BETA

Beclomethasone Dipropionate and Prednisone in the Treatment of Active UC

See original study

See summary

MSC perianal disease

Allogeneic Bone Marrow–Derived Mesenchymal Stromal Cells in Perianal Fistulas in CD

See original study

See summary

Mongersen -CD

Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease

See original study

See summary

Vercirnon-CD

Randomised clinical trial: vercirnon, an oral CCR9 antagonist,vs. placebo as induction therapy in active Crohn’s disease

See original study

See summary

2014
GEMINI III

Vedolizumab in CD previously expossed to antiTNF

See original study

See summary

UC-SUCCESS

Infliximab, azathioprine or combo in UC

See original study

See summary

PURSUIT-SC
PURSUIT-M
ADAFI

Adalimumab +/- ciprofloxacin in perianal CD

See original study

See summary

ADA in UC Japan

Adalimumab in Japanese patients with UC

See original study

See summary

FHAST-1

AST-120 (Spherical Carbon Adsorbent) in the Treatment of Perianal Fistulae in Mild-to-Moderate CD

See original study

See summary

COMMIT

Infliximab +/- methotrexate in CD

See original study

See summary

IFX/ADA postop

Infliximab vs adalimumab in postoperative recurrence in CD

See original study

See summary

5ASA dose kids

Mesalazine in pediatric UC

See original study

See summary

GROWTH-CD

New diagnosis pediatric CD different outcomes

See original study

See summary

2014
2013
MOTUS

Mesalazine in UC, one or two doses/day

See original study

See summary

MUSIC

Certolizumab in CD

See original study

See summary

IFX kids

Infliximab in paediatric UC

See original study

See summary

GEMINI I
GEMINI II
Thalidomide kids CD

Thalidomide in paediatric CD

See original study

See summary

AZA/ IFX postop

Azathioprine vs infliximab in postoperative recurrence in CD

See original study

See summary

RAPID

Azathioprine vs conventional therapy in CD

See original study

See summary

AZTEC

Azathioprine vs in newly diagnosed CD

See original study

See summary

Cipro postop

Ciprofloxacin in postop recurrence in CD

See original study

See summary

AZA +/- METRO postop

AZA +/-METRO in postop recurrence in CD

See original study

See summary

5ASA sup

5ASA suppositories in UC proctis

See original study

See summary

Cow Milk Protein exclusion diet ped-UC

Cow milk protein exclusion diet in pediatric UC

See original study

See summary

Budesonide-CD

Budesondie in Japanese patients with CD

See original study

See summary

Apheresis-CD

A randomised, double-blind, sham-controlled study of granulocyte/monocyte apheresis for moderate to severe Crohn’s disease

See original study

See summary

2012
ULTRA II
STORI

Infliximab stop in CD

See original study

See summary

EXTEND
ADA in Japanese-CD

Adalimumab in patients with CD from Japan

See original study

See summary

PODIUM

Mesalazine in UC once or twice daily

See original study

See summary

SWITCH

Infliximab switch to adalimumab in CD

See original study

See summary

IMAgINE 1

Adalimumab in paediatric CD

See original study

See summary

CERTIFI
CYSIF

Cyclosporin vs infliximab in ASUC

See original study

See summary

CORE I
IFX postop

Infliximab in postoperative recurrence in CD

See original study

See summary

ADA/AZA/5ASA postop

Adalimumab, azathioprine or 5ASA in postoperative recurrence in CD

See original study

See summary

TACRO UC

Tacrolimus in steroid dependent UC

See original study

See summary

SECUKINUMAB

Secukinumab in mode-severe CD

See original study

See summary

APHERESIS-CD

A randomised, double-blind, sham-controlled study of granulocyte/monocyte apheresis for moderate to severe Crohn’s disease

See original study

See summary

2012
2011
ULTRA I
WELCOME

Certolizumab in CD

See original study

See summary

5ASA vs budesonide-UC

5ASA vs budesonide in UC

See original study

See summary

5ASA vs budesonide-CD

5ASA vs budesonide in CD

See original study

See summary

FOS-CD

Fructo-oligosaccharides in active Crohn’s disease

See original study

See summary

2010
SONIC

Infliximab, azathioprine or combo in CD

See original study

See summary

PRECiSE III

Certolizumab in CD

See original study

See summary

PRECiSE 4

Reinduction with certolizumab in CD

See original study

See summary

ADHERE
5ASA vs AZA postop

5ASA vs AZA in CD postop recurrence

See original study

See summary

Metronidazole ointment perianal CD

Metronidazol ointment 10% in perianal CD

See original study

See summary

Fibrin glue perianal CD

Fibrin glue in perianal CD

See original study

See summary

IgG Food antigen CD

Diet intervention study in CD:IgG antibodies against food antigens

See original study

See summary

2010
2009
IFX postop

Infliximab in postop recurrence in CD

See original study

See summary

AZA/5ASA postop

AZA/5ASA in postop recurrence in CD

See original study

See summary

5ASA-MMX Asacol

Ulcerative colitis maintenance tratment with 5-ASA

See original study

See summary

2008
SUTD

Step-up vs top-down management in CD

See original study

See summary

METRO+/- AZA postop

Metronidazol +/- AZA in postop recurrence in CD

See original study

See summary

Balsalazide

Balsalazide induction in UC

See original study

See summary

Everolimus vs AZA

Everolimus vs azathioprine vs placebo in CD

See original study

 

AST-120 perianal CD

Oral Spherical Adsorptive Carbon for the Treatment of Intractable Anal Fistulas in CD

See original study

 

Clarithromycin in CD

randomized study of clarithromycin versus placebo in active Crohn’s disease

See original study

See Summary 

EPIC 1 & 2

Omega-3 Free Fatty Acids for the Maintenance of Remission in Crohn Disease

See original study

See Summary 

2008
2007
CLASSIC II
CHARM
REACH

Infliximab in paediatric CD

See original study

See summary

PRECiSE I

Certolizumab in CD

See original study

See summary

PRECiSE II

Certolizumab in CD

See original study

See summary

GAIN
Natalizumab+IFX

Safety and Tolerability of Concurrent Natalizumab Treatment for Patients with Crohn’s Disease Not in Remission While Receiving Infliximab

See original study

See summary

synbiotics postop

Synbiotics in CD for postop recurrence

See original study

See summary

Probiotics postop

Probiotics in CD for postop recurrence

See original study

See summary

DIET in CD

Probiotics in CD for postop recurrence

See original study

See summary

topical tacrolimus in PCD

Topical tacrolimus in perianal Crohn’s disease

See original study

See summary

Antibiotic combo in CD

Two-Year Combination Antibiotic Therapy With Clarithromycin, Rifabutin, and Clofazimine for Crohn’s Disease

See original study

See summary

2006
TREAT

Long-term safety data from drugs in CD

See original study

See summary

CLASSIC I
TACRO UC
probiotics postop

Probiotics in postoperative recurrence

See original study

See summary

5ASA-AZA

5ASA vs Azathioprine in UC

See original study

See summary

Half elemental diet CD

Effectiveness of an ‘half elemental diet’ as maintenance therapy for CD

See original study

See summary

Polymeric diet vs steroids

Polymeric Diet Alone Versus Corticosteroids in the Treatment of Active Pediatric Crohn’s Disease: A Randomized Controlle Open-Label Trial

See original study

See summary

2006
2005
PINCE

Mesalazine oral +/- topical in UC

See original study

See summary

ACT 1&2
LGG kids

Lactobacillus rhamnosus strain GG in paediatric CD

See original study

See summary

Ornidazol postop

Ornidazol in CD for postop recurrence

See original study

See summary

ENACT-1 & 2
Budesonide longterm-CD

Budesonide as maintenance in CD

See original study

See summary

Microparticle diet CD

Lack of efficacy of a reduced microparticle diet in a multi-centred trial of patients with active CD

See original study

See summary

2004
BUDE/PRED kids

Budesonide or prednisolone in pediatric CD

See original study

See summary

ACCENT II

Infliximab in fistulising CD

See original study

See summary

IFX +/- ciprofloxacin perianal cd

Infliximab +/- ciprofloxacin in perianal CD

See original study

See summary

5ASA/AZA postop

5ASA vs AZA in CD for postoperative recurrence

See original study

See summary

5ASA/6MP postop

5ASA vs 6MP in CD for postoperative recurrence

See original study

See summary

Aloe vera in UC

Oral aloe vera in active UC

See original study

See summary

2004
2003
CYCLO 2/4

Cycloporin 2mg/kg/d vs 4mg/kg/d in ASUC

See original study

See summary

5ASA postop

5ASA in CD for postop recurrence

See original study

See summary

Oral tacrolimus fistulizing CD

Oral tacrolimus in fistulizing CD

See original study

See summary

Steroids & Immunogenicity

Hydrocortisone IV and anti drug antibody formation

See original study

See summary

EGF enema

Epidermal Growth Factor Enemas in left side UC

See original study

See summary

Natalizumab
2002
ACCENT I
Lactobacillus postop

Lactobacillus in CD for postop recurrence

See original trial

See summary

Beclomethasone

Beclomethasone for UC

See original trial

See summary

Budesonide-CD

Budesonide once or twice daily in CD

See original trial

 

2002
2001
CICLO vs STEROIDS

Cyclosporine vs steroids in ASUC

See original study

See summary

5ASA foam enema

Mesalazine foam enema (Salofalk foam) for distal ulcerative colitis

See original study

See summary

2000
MCP kids

Mercaptopurine in pediatric CD

See original study

See summary

MCP-MTX-5ASA

Mercaptopurine, methotrexate or mesalazine in IBD

See original study

See summary

MTX-CD

Methotrexate in CD

See original study

See summary

5ASA postop

5ASA in CD for postoperative recurrence

See original study

See summary

5ASA sup

5ASA suppositories maintenance in UC proctitis

See original study

See summary

1998
Budesonide vs mesalazine-cd

Infliximab for induction of remission in CD

See original study

See summary

1998
1997
IFX-CD

 Infliximab for induction of remission in CD

See original study

See summary

1996
Methotrexate- UC

Methotrexate in active UC

See original study

See summary

Omega3 & Low carbohydrate diet CD

Omega-3 Fatty Acids and Low Carbohydrate Diet for Maintenance of Remission in CD

See original study

See summary

1996
1995
IFX-cA2

CA2 single infusion (IFX) efficacy in CD

See original study

See summary

METRO postop

Metronidazol in CD postoperative recurrence

See original study

See summary

MTX- CD

Methotrexate in CD 

See original study

See summary

AZA-CD

Azathioprine in CD

See original study

See summary

Elimination diet-UC

Elimination diet in the management of patients with ulcerative colitis

See original study

See summary

1994
Budesonide -CD

Oral budesonide in CD

See original study

See summary

Hyperbaric oxygen-perianal CD

Hyperbaric oxygen in perianal CD

See original study

Oral 5ASA -CD

Oral 5ASA in ileocolonic and colonic CD

See original study

1994
1993
Mesalamine CD

Mesalamine for CD a 16-week trial

See original study

Prednisone +/- Azathioprine- CD

Prednisone monotherapy or combined with azathioprine in CD

See original study

See summary

1992
1992
1991
fecal stream postop

Fecal stream in CD postoperative recurrence

See original study

See summary

Metronidazole-CD

Double blind, placebo controlled trial of metronidazole

in Crohn’s disease

See original study

See summary

1990
Smoking & postop recurrence

Fecal stream in CD postoperative recurrence

See original study

See summary

Slow release 5ASA in CD

Slow-Release 5-Amino-Salicylic Acid (Pentasa®) for the Treatment of Active Crohn’s Disease

See original study

 

1990
1987
5ASA-CD

 5ASA in CD for induction of remission

See original study

See summary

Incision +/- fistulotomy pCD

Incision alone or incision + fistulotomy in perianal CD

See original study

 

1986
1986
1985
fecal stream postop

Fecal stream in CD postoperative recurrence

See original study

See summary

Diet trial CD

Unrefined carbohydrate fibre rich diet vs diet with exclusion of specific foods in the maintenance of remission in CD

See original study

See summary

Low residue diet CD

Low residue or normal diet in Crohn’s disease

See original study

See summary

EEN in CD

Controlled trial comparing prednisolone with an elemental diet plus non-absorbable antibiotics in active Crohn’s disease

See original study

See summary

1984
4ASA enemas

4ASA enemas for distal ulcerative colitis induction

See original study

See summary

sulfasalazine & 6-methylprednisolone in CD

European Cooperative Crohn’s Disease Study (ECCDS): results of drug treatment

See original study

See summary

1984
1983
Supplemented oral nutrition CD

Supplemented oral nutrition in CD

See original study

See summary

1982
TRANEXAMIC

Tranexamic acid in ulcerative colitis

See original study

See summary

1982
1981
5ASA enema

5ASA enema in ulcerative colitis

See original study

See summary

1980
Sulphapyridine vs 5-ASA

Sulphapyridine vs 5-ASA in proctitis

See original study

See summary

Mercaptopurine-CD

Mercaptopurine for induction of remission in CD

See original study

See summary

1980
1979
Pred- AZA-Sulphapyridine in CD

Prednisone, azathioprine and sulphasalazine in CD

See original study

See summary

1978
Prednisone single/multiple doses UC

Oral Prednisolone as Single vs Multiple Daily Doses for Active UC

See original study

See summary

Steroids-CD

Steroids for maintenance of remission in CD

See original study

See summary

1978
1977
Metronidazol UC

Metronidazole in the treatment of chronic proctitis

See original study

See summary

1974
Azathioprine UC

Azathioprine for induction of remission in UC

See original study

See summary

Azathioprine CD

Azathioprine for induction of remission in CD

See original study

See summary

Salazopyrin CD

Salazopyrin for induction of remission in CD

See original study

See summary

1974
1973
Sulphasalazine UC

Sulphasalazine for maintenance of remission in UC

See original study

See summary

1972
1972
1971
Azathioprine-CD

Azathioprine for induction of remission in CD

See original study

See summary

Azathioprine-CD II

Azathioprine for maintenance of remission in CD

See original study

See summary

1968
1968
1967
1966
1966
1965
Prednisone maintenance UC

Prednisone as maintenance therapy in UC

See original study

See summary

Sulphasalazine maintenance UC

Sulphasalazine as maintenance therapy in UC

See original study

See summary

Various diets UC

A Controlled Therapeutic Trial of Various Diets in Ulcerative Colitis

See original study

See summary

1964
1964
1963
1962
Prednisone in UC

Prednisone in UC outpatients

See original study

See summary

Steroids vs sulphasalazine in UC

Comparison Of Corticosteroid And Sulphasalazine Therapy In UC

See original study

See summary

Sulphasalazine in UC

Sulphasalazine And Salicylazosulphadimidine in UC

See original study

See summary

Steroid sup UC proctitis

prednisolone-21-phosphate suppositories in UC proctitis

See original study

See summary

1962
1961
1960
corticosteroids in uc

Systemic And Local Corticosteroid Therapy In Ulcerative Colitis

See original study

See summary

oral steroids vs topical vs Salazopyrin

Prednisone, Salazopyrin and Topical Hydrocortisone Hemisuccinate in UC

See original study

See summary

1960
1959
Cortisone and corticotrophin in uc

Cortisone and corticotrophin admitted patients with active UC

See original study

See summary

1958
Topical Hydrocortisone

Topical Hydrocortisone Hemisuccinate Sodium for induction of remission UC

See original study

See summary

Topical Hydrocortisone II

Topical Hydrocortisone Hemisuccinate Sodium for induction of remission UC

See original study

See summary

1958
1955
cortisone in asuc

Cortisone in acute severe UC

See original study

See summary

Any suggestions?

If you have any suggestion of trials or studies to add, changes or corrections of any error, feel free to write me here

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