Evidence Corner
STUDIES ORGANIZED BY CATEGORIES
In the evidence corner these studies, instead of being organized by dates, are organized by other categories (drug class, surgery…).
The summaries in this section are presented in a much more reduced way.
Type of drug
5ASA
Thiopurines
METHOTREXATE
INFLIXIMAB
ADALIMUMAB
certolizumab
GOLIMUMAB
VEDOLIZUMAB
USTEKINUMAB
TOFACITINIB
FILGOTINIB
UPADACITINIB
RISANKIZUMAB
MIRIKIZUMAB
OZANIMOD
ETRASIMOD
Paediatric
Ultra summary
COMBINE
MCP kids
BUDE/PRED kids
LGG kids
IMAgINE
Thalidomide kids CD
IFX kids
5ASA kids
GROWTH-CD
Thalidomide kids UC
GOLI Kids
PAILOT
PRASCO
PRESENCE
UNISTAR
ENVISION I
TISkids
HUBBLE
VEDOKIDS
Paediatric
Conception, pregnancy, postpartum & lactation
2024 Thiopurine during pregnancy and intrahepatic cholestasis
Thiopurine Metabolite Shunting in Late Pregnancy Increases the Risk of Intrahepatic Cholestasis of Pregnancy in Women With Inflammatory Bowel Disease, and Can be Managed With Split Dosing
2024 Updates on IBD management from preconception to pregnancy & lactation
Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation
2024 pregnancy outcomes in the ozanimod program in uc, cd and multiple sclerosis
Pregnancy Outcomes in the Ozanimod Clinical Development Program in Patients With Ulcerative Colitis, Crohn’s Disease, and Relapsing Multiple Sclerosis
2024 Safety of vedolizumab & ustekinumab vs antiTNF in IBD pregnant patients
Safety of vedolizumab and ustekinumab compared with anti-TNF in pregnant women with inflammatory bowel disease
2023 Immunological effects & safety of rotavirus vaccination after antenatal exposure to biologics
Immunological effects and safety of live rotavirus vaccination after antenatal exposure to immunomodulatory biologic agents: a prospective cohort study from the Canadian Immunization Research Network
2023 ECCO guideline on sexuality, fertility, pregnancy & lactation
European Crohn’s and Colitis Guidelines on Sexuality, Fertility, Pregnancy, and Lactation
2023 Tofactinib in plasma & breastmilk of women with UC
Tofacitinib concentrations in plasma and breastmilk of a lactating woman with ulcerative colitis
2023 Maternal & neonatal outcomes in vedolizumab & ustekinumab exposed
Maternal and Neonatal Outcomes in Vedolizumab and Ustekinumab Exposed Pregnancies: Results from the PIANO registry
2023 ovarian reserve function & IBD meta-analysis
Inflammatory bowel disease can reduce ovarian reserve function in women: A systematic review and meta-analysis
2022 biologics & safety during pregnancy meta-analysis
Biologics for Inflammatory Bowel Disease and Their Safety in Pregnancy: A Systematic Review and Meta-analysis
2022 ustekinumab exposure & pregnancy outcomes
Pregnancy outcomes following periconceptional or gestational exposure to ustekinumab: Review of cases reported to the manufacturer’s global safety database
2022 steroid exposure & pregnancy outcomes
Exposure to corticosteroids in pregnancy is associated with adverse perinatal outcomes among infants of mothers with inflammatory bowel disease: results from the PIANO registry
2022 children born to mothers with IBD & infectious risk
Day Care Attendance and Infectious Complications in Children Born to Mothers With Inflammatory Bowel Disease
2022 postpartum disease activity meta-analysis
Risk Factors for Postpartum Disease Activity in Women With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
2022 infliximab & adalimumab & pregnancy outcomes meta-analysis
Comparative safety of infliximab and adalimumab on pregnancy outcomes of women with inflammatory bowel diseases: a systematic review & meta-analysis
2021 biologic use & risk of infantile infections meta-analysis
Biologics During Pregnancy in Women With IBD and Risk of Infantile Infections: A Systematic Review and Meta-Analysis
2021 pregnancy & neonatal outcomes in exposed to biologics & thiopurines
Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease
2021 adverse neonatal outcomes with Maternal IBD meta-analysis
The Risk of Adverse Neonatal Outcomes With Maternal Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
2021 disease activity on pregnancy outcomes meta-analysis
The Influence of Disease Activity on Pregnancy Outcomes in Women With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
2021 thiopurines & pregnancy outcomes meta-analysis
Association between Thiopurines Use and Pregnancy Outcomes in Female Patients with Inflammatory Bowel Disease: A Meta-Analysis
2019 Pregnant women on biologics & infant response to vaccines
Use of Biologic Therapy by Pregnant Women with Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines
2019 Preventive Health Care Among Postpartum IBD women-PIANO registry
Preventive Health Care Among Postpartum Women With Inflammatory Bowel Disease: Results From the PIANO Registry
2019 Pregnancy Clinical care pathway in IBD
Inflammatory Bowel Disease in Pregnancy Clinical Care Pathway: A Report From the American Gastroenterological Association IBD Parenthood Project Working Group
2018 Infants breastfed by women on biologic therapy for IBD & infections
Exposure Concentrations of Infants Breastfed by Women Receiving Biologic Therapies for Inflammatory Bowel Diseases and Effects of Breastfeeding on Infections and Development
2018 Pregnancy outcomes from 13-year TREAT registry
Pregnancy Outcomes Reported During the 13-Year TREAT Registry: A Descriptive Report
2018 Flexible sigmoidoscopy in pregnant patients
Safety of Flexible Sigmoidoscopy in Pregnant Patients with Known or Suspected Inflammatory Bowel Disease
2017 inadequate gestational weight gain in IBD pregnant-Norway
Inadequate Gestational Weight Gain, the Hidden Link Between Maternal IBD and Adverse Pregnancy Outcomes: Results from the Norwegian Mother and Child Cohort Study
2017 inadequate gestational weight gain in IBD pregnant-US
Inadequate Gestational Weight Gain Predicts Adverse Pregnancy Outcomes in Mothers with Inflammatory Bowel Disease: Results from a Prospective US Pregnancy Cohort
2017 drug safety in IBD pregnant
Drug Safety and Risk of Adverse Outcomes for Pregnant Patients With Inflammatory Bowel Disease
2017 vedolizumab during pregnancy
Vedolizumab exposure in pregnancy: outcomes from clinical studies in inflammatory bowel disease
2014 antiTNF are safe during pregnancy meta-analysis
Anti-TNFα Therapies Are Safe During Pregnancy in Women with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
2014 disease activity & conception meta-analysis
Meta-analysis: the impact of disease activity at conception on disease activity during pregnancy in patients with inflammatory bowel disease
2007 IBD influence on pregnancy meta-analysis
A meta-analysis on the influence of inflammatory bowel disease on pregnancy
Fertility, sexuality & paternal outcomes in men with IBD
2024 male fertility & reproductive outcomes- meta-analysis
Prevalence of Sexual Dysfunction in Inflammatory Bowel Disease: Systematic Review and Meta-analysis
2023 male fertility & reproductive outcomes- meta-analysis
Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-analysis
2022 Prevalence & risk factors of erectile dysfunction in IBD meta-analysis
The Prevalence and Associated Risk Factors of Erectile Dysfunction in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-analysis
2021 Prevalence & risk factors for sexual dysfunction meta-analysis
Prevalence and risk factors of sexual dysfunction in patients with inflammatory bowel disease: systematic review and meta-analysis
2021 paternal exposure to immunossuppressants or biologics & birth outcomes
Paternal Exposure to Immunosuppressive and/or Biologic Agents and Birth Outcomes in Patients With Immune-Mediated Inflammatory Diseases
2020 Sexual function, fertility, medication safety & prostate cancer in men with IBD
Men With Inflammatory Bowel Disease: Sexual Function, Fertility, Medication Safety, and Prostate Cancer
2019 Sexual dysfunction in IBD-meta-analysis
Inflammatory Bowel Diseases Were Associated With Risk of Sexual Dysfunction in Both Sexes: A Meta-analysis
2019 IBD therapies & men fertility- meta-analysis
Inflammatory Bowel Disease Therapies Adversely Affect Fertility in Men- A Systematic Review and Meta-analysis
Fertility, sexuality & paternal outcomes in men with IBD
Post operative recurrence in CD
ULTRA SUMMARY
SUPREME-CD
IFX postop III
APPRECIA
TOPPIC
PREVENT
VSL3 postop
IFX vs ADA postop
AZA vs METRO postop
AZA/IFX postop
ADA/AZA/5ASA postop
CIPRO postop
IFX postop II
5ASA vs AZA postop
IFX postop
METRO +/- AZA postop
Probiotics postop II
Synbiotics postop
Probiotics postop
Ornidazol postop
6mp/5ASA postop
5ASA vs AZA postop
5ASA postop II
Lactobacillus postop
5ASA postop
METRO postop
Fecal stream diversion postop II
Smoking and postop
Fecal stream diversion postop
UC proctitis
ULTRA SUMMARY
See summary
2020 tacro/beclo
2017 topic tacro
2013 5ASA sup
2000 5ASA sup
1984 4ASA enema
1980 Sulphapyridine vs 5ASA
1977 Metronidazol
1962 Steroid Suppositories
1958 Topical Hydrocortisone
1958 topical hydrocortisone II
UC proctitis
Perianal disease
ULTRA SUMMARY
Any suggestions?
If you have any suggestion of trials or studies to add, changes or corrections of any error, feel free to write me here
Illustrations by Cristina Gros Content creator and development Beatriz Gros
